How new research has revealed Fertility hope for PCOS patients

How new research has revealed Fertility hope for PCOS patients

Scientists at the French National Institute of Health and Medical Research have reported that a simple hormone imbalance could be the cause of polycystic ovary syndrome (PCOS) and could potentially be reversed with the use of a common IVF drug.

PCOS affects approximately 1 in 5 women worldwide and three quarters of women suffering will experience fertility problems. The condition is characterised by increased levels of testosterone, ovarian cysts, ovulation problems and irregular or infrequent menstrual cycles. It is by far the most common hormonal problem affecting women of reproductive age.

The study revealed that there could be a link between increased levels of anti-Müllerian hormone (AMH) in pregnant women who have PCOS and likelihood of their children developing PCOS, suggesting that a prenatal exposure to increased levels of AMH may be an underlying cause of PCOS.

To test this, the scientists experimented by injecting pregnant mice with AMH and discovered that their offspring developed many of the characteristics associated with PCOS i.e. delayed puberty, infrequent ovulation, delays in falling pregnant and reduced number of offspring.

In an even more remarkable breakthrough, the scientists were able to reverse the effect in the mice using a common IVF drug, used routinely during a woman’s IVF treatment to control hormone levels.

Clinical trails are expected to begin within the next year and if successful, this revolutionary study could provide hope to women with PCOS who are suffering from fertility issues.

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FAQs about improving natural fertility

Will stress affect my ability to get pregnant?

Yes, chronic stress can impact fertility by disrupting hormonal balance and ovulation patterns. Managing stress through relaxation techniques, regular exercise, adequate sleep, and mindfulness practices may help optimise your chances of conception. Consider speaking with a counsellor if stress feels overwhelming.

How does my partner's health affect our fertility?

Sperm health accounts for about 40% of conception challenges. Your partner can improve sperm health by maintaining a healthy weight, avoiding excessive heat exposure (hot tubs, saunas, tight clothing), limiting alcohol, quitting smoking, managing stress, and taking a multivitamin with antioxidants. Sperm takes about 3 months to develop, so lifestyle changes need time to show results.

When during my cycle am I most fertile?

Your fertile window typically spans 5-6 days, ending on ovulation day. For a regular 28-day cycle, this usually falls between days 10-15, with peak fertility 1-2 days before ovulation. Track your cycle using ovulation predictor kits, basal body temperature, or cervical mucus changes to identify your unique pattern. Having intercourse every 1-2 days during this window optimises your chances.