Can vitamin D affect follicular development and egg maturity?

Can vitamin D affect follicular development and egg maturity?

A recent study published in reproduction and sterility has shed more light into the important role vitamin D plays on our fertility.

We’ve posted in the past about the importance of vitamin D and how it impacts sperm health and embryo quality. Recently, researchers from Oregon Health and Science University and Portland State University in the United States have revealed a strong link between vitamin D and mitochondrial biogenesis in developing eggs.

What does this mean?

Essentially, human eggs will develop and mature in follicles located in the ovary. The growth and development is controlled by local factors in addition to mediating actions of gonadotropins (the FSH injections you have to take during your cycle). The studies have determined that vitamin D plays a key role in helping to regulate physiological functions that control reproduction and influence the metabolism and signalling pathways in the ovary.

In mouse studies, it was discovered that mice who were fed a diet that was deficient in vitamin D had fewer mature eggs, impaired follicular development and estrogen biosynthesis was disrupted due to poor gene expression.

In contrast, vitamin D3 supplementation helped to promote granulosa cell proliferation. This is important because granulosa cells form the single layer surrounding your developing eggs, and are involved with the production of sex steroids which impact the quality of your eggs.

Fertility First has recognised the importance of sufficient vitamin D levels in our male and female patients trying to conceive for over 10 years. As a result, our clinic will routinely test the vitamin D levels in all our patients as part of our preliminary assessment.

And where can you find vitamin D?

Foods that are rich sources of vitamin D include fatty fish such as tuna and salmon, cheese, egg yolks and orange juice. Vitamin D can also be found in mushrooms exposed to sunlight (some are commercially available), and you can also help boost your vitamin D intake by stepping outside and spending about 10-30 minutes in the sunshine. For recommended guidelines for spending time in the sun to boost your vitamin D levels, you may want to check the resources on the Cancer Council’s website.

Looking for more personalised information to assist with your fertility journey? Contact us to schedule a consultation with our expert team.

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FAQ

How does Fertility First keep fertility treatment and IVF costs down?

As a Doctor-owned Medical Practice, our fertility and IVF treatment costs do not need to cover overheads and/or shareholder dividends, all of which have to come out of the income derived from patients’ treatment cycle fees at other fertility clinics in Sydney.

What is the NSW fertility treatment rebates?

From the 1st October 2022, the NSW Government announced a rebate of $2,000 in OOP expenses for all eligible patients. Fertility First is pleased to support the NSW Government’s fertility rebate at our Sydney fertility clinic.

What makes Fertility First different to other Sydney fertility clinics?

Fertility First is privately owned, which means we can place more focus on our patients. We offer a holistic approach to fertility and believe that it’s important to minimise the invasiveness of the fertility testing process and only carry out the necessary investigations, maximising your chance of a successful outcome. We offer extensive preliminary fertility testing, including Halosperm Assay.

We were one of the first Sydney fertility clinics to offer a donor sperm and donor egg program, thanks to our partnership with Central IVF.

How do I choose the best fertilty clinic for me?

Choosing the right fertility clinic in Sydney is a very important decision. You should consider factors like success rates, clinic location and appointment times, fertility treatment costs, repor with the Fertility Specialist and what treatment options are available.

Does Fertility First offer preliminary fertility testing?

Yes. We offer a range of fertility testing for both males and females. We aim to have fertility test results back within 2 to 3 weeks, which means, unless any assessment of the fallopian tubes is required, fertility treatment options can then be considered.

Does Fertility First offer treatment for same sex couples and singles?

Yes. Fertility First offers a range of fertility treatments that are suitable for same sex couples and singles, including our donor sperm program. See our fertility treatment page for a full guide.

Does Fertility First offer Medicare rebates?

Yes. In order to assist you with a Medicare rebate for your fertility treatment, you will need a current referral to Fertility First.

Note: GP referrals are valid for 12 months, and specialist referrals are valid for 3 months.

Does Fertility First offer IVF treatment?

Yes. IVF treatment is offered to suitable patients after preliminary testing.