DNA damage and sperm

DNA damage and sperm

It has been well documented that oxidative stress damage can have a significant effect on sperm and as a result, will impact negatively on a man’s fertility.

The genetic integrity of sperm is essential for not only normal fertilisation and embryo development, but research has also revealed that high levels of DNA fragmentation in sperm have been linked to early pregnancy loss, miscarriage, and abnormalities in the offspring including an increased vulnerability to childhood cancer.

A recent study published at the beginning of October this year has focused on determining where the oxidative DNA damage is occurring and unexpectedly, the research has revealed that the damage is in fact targeted at specific regions of the paternal genome. What does this mean exactly? It means that the DNA damage isn’t occurring randomly, as once thought, however it is in fact targeting specific chromosomes that are particularly vulnerable to oxidative stress.

By uncovering this new information, it could potentially assist in improving the quality of treatment for men undergoing IVF and be of great value to understanding the effects of paternal exposure to environmental toxicants that we know are a major cause of DNA damage.

Fertility First has recognised the importance of sperm health and genetic integrity when it comes to male fertility and healthy pregnancies, and has been testing for sperm DNA damage in patients since 2006. Our clinic will perform routine fertility testing on all our male patients, including potential donors before fertility treatment commences to give you the best chance of being able to achieve a healthy pregnancy.

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FAQ

How does Fertility First keep fertility treatment and IVF costs down?

As a Doctor-owned Medical Practice, our fertility and IVF treatment costs do not need to cover overheads and/or shareholder dividends, all of which have to come out of the income derived from patients’ treatment cycle fees at other fertility clinics in Sydney.

What is the NSW fertility treatment rebates?

From the 1st October 2022, the NSW Government announced a rebate of $2,000 in OOP expenses for all eligible patients. Fertility First is pleased to support the NSW Government’s fertility rebate at our Sydney fertility clinic.

What makes Fertility First different to other Sydney fertility clinics?

Fertility First is privately owned, which means we can place more focus on our patients. We offer a holistic approach to fertility and believe that it’s important to minimise the invasiveness of the fertility testing process and only carry out the necessary investigations, maximising your chance of a successful outcome. We offer extensive preliminary fertility testing, including Halosperm Assay.

We were one of the first Sydney fertility clinics to offer a donor sperm and donor egg program, thanks to our partnership with Central IVF.

How do I choose the best fertilty clinic for me?

Choosing the right fertility clinic in Sydney is a very important decision. You should consider factors like success rates, clinic location and appointment times, fertility treatment costs, repor with the Fertility Specialist and what treatment options are available.

Does Fertility First offer preliminary fertility testing?

Yes. We offer a range of fertility testing for both males and females. We aim to have fertility test results back within 2 to 3 weeks, which means, unless any assessment of the fallopian tubes is required, fertility treatment options can then be considered.

Does Fertility First offer treatment for same sex couples and singles?

Yes. Fertility First offers a range of fertility treatments that are suitable for same sex couples and singles, including our donor sperm program. See our fertility treatment page for a full guide.

Does Fertility First offer Medicare rebates?

Yes. In order to assist you with a Medicare rebate for your fertility treatment, you will need a current referral to Fertility First.

Note: GP referrals are valid for 12 months, and specialist referrals are valid for 3 months.

Does Fertility First offer IVF treatment?

Yes. IVF treatment is offered to suitable patients after preliminary testing.