Recurrent miscarriage and DNA fragmentation

Recurrent miscarriage and DNA fragmentation

Experiencing a miscarriage can be both emotionally and physically debilitating. Experiencing recurrent miscarriages can not only add to the already traumatic situation, but it can also leave patients feeling frustrated and searching for answers.

There have been previous studies that have identified a link between DNA damage in a man’s sperm and recurrent miscarriage, and the most recent study coming out of the UK at the Imperial College London adds to it.

So, is there a link between miscarriage and DNA fragmentation?

The researchers analysed the sperm quality of over 50 men whose partners had suffered from recurrent miscarriages and compared the results with men whose partners had not experienced miscarriages. The sperm from the recurrent miscarriage group was found to have significantly higher levels of DNA damage compared to the other group- in fact almost twice the amount!

It has been thought that the DNA damage in sperm may be caused by reactive oxygen species (ROS) that are created by semen cells to protect the sperm from infections and bacteria, however high concentrations they have been shown to have a negative effect in sperm cell DNA. When the researchers looked at levels of ROS in the semen samples from the recurrent miscarriage group, it was found that the levels had a four-fold increase compared to that of the other group of men.

Fertility First has recognised the importance of sperm health when it comes to fertility and healthy pregnancies and has been testing for sperm DNA damage in patients for over 13 years.

Our clinic will perform routine testing on all our male patients, including potential donors before fertility treatment commences to give you the best chance of being able to achieve a healthy pregnancy.

For more information on DNA fragmentation testing or our donor sperm program, please contact our clinic on (02) 9586 3311 and speak to one of our friendly staff members.

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FAQ

How does Fertility First keep fertility treatment and IVF costs down?

As a Doctor-owned Medical Practice, our fertility and IVF treatment costs do not need to cover overheads and/or shareholder dividends, all of which have to come out of the income derived from patients’ treatment cycle fees at other fertility clinics in Sydney.

What is the NSW fertility treatment rebates?

From the 1st October 2022, the NSW Government announced a rebate of $2,000 in OOP expenses for all eligible patients. Fertility First is pleased to support the NSW Government’s fertility rebate at our Sydney fertility clinic.

What makes Fertility First different to other Sydney fertility clinics?

Fertility First is privately owned, which means we can place more focus on our patients. We offer a holistic approach to fertility and believe that it’s important to minimise the invasiveness of the fertility testing process and only carry out the necessary investigations, maximising your chance of a successful outcome. We offer extensive preliminary fertility testing, including Halosperm Assay.

We were one of the first Sydney fertility clinics to offer a donor sperm and donor egg program, thanks to our partnership with Central IVF.

How do I choose the best fertilty clinic for me?

Choosing the right fertility clinic in Sydney is a very important decision. You should consider factors like success rates, clinic location and appointment times, fertility treatment costs, repor with the Fertility Specialist and what treatment options are available.

Does Fertility First offer preliminary fertility testing?

Yes. We offer a range of fertility testing for both males and females. We aim to have fertility test results back within 2 to 3 weeks, which means, unless any assessment of the fallopian tubes is required, fertility treatment options can then be considered.

Does Fertility First offer treatment for same sex couples and singles?

Yes. Fertility First offers a range of fertility treatments that are suitable for same sex couples and singles, including our donor sperm program. See our fertility treatment page for a full guide.

Does Fertility First offer Medicare rebates?

Yes. In order to assist you with a Medicare rebate for your fertility treatment, you will need a current referral to Fertility First.

Note: GP referrals are valid for 12 months, and specialist referrals are valid for 3 months.

Does Fertility First offer IVF treatment?

Yes. IVF treatment is offered to suitable patients after preliminary testing.