Autism-linked gene undergoes changes in sperm after drug use

Autism-linked gene undergoes changes in sperm after drug use

Healthy lifestyle changes are always strongly encouraged when one is about to embark on a fertility journey, and research is highlighting the importance now more than ever.

Over the past decades, there has been a huge number of studies showing just how important it is to quit smoking, limit alcohol consumption, and improve the overall health of the patients who are looking at trying to start a family. The same goes for drug use.

A recent study from Duke University in North Carolina has revealed that a specific gene associated with autism appears to undergo significant changes in the sperm of men who use cannabis. The change occurs through a process known as DNA methylation and there’s a strong possibility that these changes can be passed onto the offspring of the men.

This is the first study that demonstrates a link between the changes of a gene that has previously been implicated in autism, and the association with male cannabis use.

The gene affected is not only involved with autism, but it also is involved with neurological conditions such as schizophrenia and post-traumatic stress disorder.

Although the sample size was relatively small and the researchers couldn’t find a definitive link between the use of marijuana and autism, the possible connection and the evidence showing the impact the drug has on gene expression definitely warrants further investigation, especially given there is an increasing push locally to legalise the use of the drug.

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FAQs about improving natural fertility

Will stress affect my ability to get pregnant?

Yes, chronic stress can impact fertility by disrupting hormonal balance and ovulation patterns. Managing stress through relaxation techniques, regular exercise, adequate sleep, and mindfulness practices may help optimise your chances of conception. Consider speaking with a counsellor if stress feels overwhelming.

How does my partner's health affect our fertility?

Sperm health accounts for about 40% of conception challenges. Your partner can improve sperm health by maintaining a healthy weight, avoiding excessive heat exposure (hot tubs, saunas, tight clothing), limiting alcohol, quitting smoking, managing stress, and taking a multivitamin with antioxidants. Sperm takes about 3 months to develop, so lifestyle changes need time to show results.

When during my cycle am I most fertile?

Your fertile window typically spans 5-6 days, ending on ovulation day. For a regular 28-day cycle, this usually falls between days 10-15, with peak fertility 1-2 days before ovulation. Track your cycle using ovulation predictor kits, basal body temperature, or cervical mucus changes to identify your unique pattern. Having intercourse every 1-2 days during this window optimises your chances.