Vitamin D supplementation and Assisted Reproductive Technology

Vitamin D supplementation and Assisted Reproductive Technology

Research presented at ESHRE this week has focused on the significance vitamin D has in the area of reproductive health.

Italian scientists presented an interim analysis of a randomised trial, looking at vitamin D levels and how supplementation can affect clinical pregnancy rates. Although the sample size wasn’t large enough to find a difference in clinical pregnancy rate per cycle, it showed a significantly higher rate in good quality embryos produced by women who took a vitamin D supplement.

Japanese scientists focused their research on the effect vitamin D has on unbalanced maternal immune tolerance, which can result in implantation failure and miscarriage. They found that sufficient vitamin D levels in women could potentially prevent maternal immune rejection of the embryo, resulting in a successful pregnancy.

Fertility First has recognised the importance of sufficient vitamin D levels in both our male and female patients trying to conceive. Our clinic has routinely tested the vitamin D levels in all our patients as part of our preliminary assessment and has been doing so for over 10 years.

Foods that are rich sources of vitamin D include fatty fish such as tuna and salmon, cheese, egg yolks and orange juice.

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FAQs about improving natural fertility

Will stress affect my ability to get pregnant?

Yes, chronic stress can impact fertility by disrupting hormonal balance and ovulation patterns. Managing stress through relaxation techniques, regular exercise, adequate sleep, and mindfulness practices may help optimise your chances of conception. Consider speaking with a counsellor if stress feels overwhelming.

How does my partner's health affect our fertility?

Sperm health accounts for about 40% of conception challenges. Your partner can improve sperm health by maintaining a healthy weight, avoiding excessive heat exposure (hot tubs, saunas, tight clothing), limiting alcohol, quitting smoking, managing stress, and taking a multivitamin with antioxidants. Sperm takes about 3 months to develop, so lifestyle changes need time to show results.

When during my cycle am I most fertile?

Your fertile window typically spans 5-6 days, ending on ovulation day. For a regular 28-day cycle, this usually falls between days 10-15, with peak fertility 1-2 days before ovulation. Track your cycle using ovulation predictor kits, basal body temperature, or cervical mucus changes to identify your unique pattern. Having intercourse every 1-2 days during this window optimises your chances.