Saizen Instructions

Instructions for Saizen

The following information is a general guide only. Please follow specific dose and usage instructions from Fertility First nursing staff at the time of treatment.

Saizen is an injection used in IVF/ICSI cycles

Saizen MUST be stored in the refrigerator between 2°C and 8°C

Do no put in freezer

Do not use Saizen after the expiry date.

If you are taking high doses of corticosteroids (eg prednisone) please advise Dr Clark or the nursing staff.

Step 1: Preparation

Wash and dry your hands thoroughly

Assemble everything you will need.

Find a clean area and lay everything out.

  • 2x alcohol swabs
  • 1x solvent vial
  • 1x powder vial
  • 1x 3ml syringe
  • 1x 21G (green) needle for reconstitution
  • 1x 27G (grey) needle for subcutaneous injection

Step 2: Draw up and mixing

Remove the protective cap from the powder the solvent vial.

Attach the 21G (green) needle for reconstitution to the syringe and draw up 2ml of solvent.

Slowly inject the solvent into the glass vial (NOT directly into the powder as this will make it froth.)

Allow solvent to slowly mix into the powder. You may gently swirl or rock the vial but DO NOT SHAKE.

Once dissolved, withdraw 1ml of solution (you may need to turn the bottle upside down to do this) then remove the needle from the vial and replace with the 27G (grey) needle for subcutaneous injection.

Step 3: Injection

Saizen is given as a subcutaneous injection (under your skin) in the lower abdominal area.

Clean the injection area with an alcohol swab.

Pinch a fold of skin between your thumb and forefinger and insert the needle fully at a 90° angle of the syringe

Keep the needle in the skin for 10 seconds after injecting and then withdraw the needle and discard immediately into your sharps container.

Keep the remaining mixture for the next day’s injection refrigerated.